{"product_id":"hgh-fragment-176-191","title":"HGH Fragment 176-191","description":"\u003cp data-start=\"131\" data-end=\"525\"\u003e\u003cstrong data-start=\"131\" data-end=\"166\"\u003eHGH Fragment 176-191 (AOD-9604)\u003c\/strong\u003e is a synthetic peptide corresponding to amino acids \u003cstrong data-start=\"219\" data-end=\"285\"\u003e176–191 of the C-terminal region of human growth hormone (hGH)\u003c\/strong\u003e. This region has been identified in research as the segment responsible for many of the \u003cstrong data-start=\"374\" data-end=\"412\"\u003elipolytic (fat-metabolism) effects\u003c\/strong\u003e of growth hormone, while lacking the domains associated with \u003cstrong data-start=\"474\" data-end=\"524\"\u003eIGF-1 stimulation or anabolic growth signaling\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp data-start=\"527\" data-end=\"964\"\u003eThe peptide consists of \u003cstrong data-start=\"551\" data-end=\"569\"\u003e16 amino acids\u003c\/strong\u003e and is designed to selectively interact with metabolic pathways involved in \u003cstrong data-start=\"646\" data-end=\"689\"\u003elipolysis and inhibition of lipogenesis\u003c\/strong\u003e. Preclinical studies have demonstrated that the fragment can \u003cstrong data-start=\"751\" data-end=\"860\"\u003estimulate the breakdown of stored triglycerides in adipose tissue while reducing the formation of new fat\u003c\/strong\u003e, without producing the systemic endocrine effects typically associated with full-length growth hormone.\u003c\/p\u003e\n\u003cp data-start=\"966\" data-end=\"1253\"\u003eBecause the fragment does not significantly increase circulating \u003cstrong data-start=\"1031\" data-end=\"1047\"\u003eIGF-1 levels\u003c\/strong\u003e, it has been investigated as a targeted approach to studying \u003cstrong data-start=\"1109\" data-end=\"1159\"\u003efat metabolism and body-composition regulation\u003c\/strong\u003e. The peptide is commonly referred to as \u003cstrong data-start=\"1200\" data-end=\"1212\"\u003eAOD-9604\u003c\/strong\u003e in pharmaceutical and research contexts.\u003c\/p\u003e\n\u003cp data-start=\"1255\" data-end=\"1423\"\u003eHGH Fragment 176-191 is typically produced via \u003cstrong data-start=\"1302\" data-end=\"1342\"\u003esolid-phase peptide synthesis (SPPS)\u003c\/strong\u003e and supplied in \u003cstrong data-start=\"1359\" data-end=\"1379\"\u003elyophilized form\u003c\/strong\u003e for stability during storage and transport.\u003c\/p\u003e","brand":"EvoX Biotech Supplies LLC","offers":[{"title":"2mg","offer_id":46592445481145,"sku":null,"price":25.0,"currency_code":"USD","in_stock":true},{"title":"10 vials with 2mg","offer_id":46592444268729,"sku":null,"price":175.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0688\/1329\/1705\/files\/HGHFragment176-191.jpg?v=1773013484","url":"https:\/\/evoxbiolabs.com\/products\/hgh-fragment-176-191","provider":"EvoX Biotech Supplies LLC","version":"1.0","type":"link"}