{"product_id":"hgh-fragment-176-191-copy","title":"SS-31 (Elamipretide)","description":"\u003cp data-start=\"107\" data-end=\"439\"\u003e\u003cstrong data-start=\"107\" data-end=\"131\"\u003eSS-31 (Elamipretide)\u003c\/strong\u003e is a synthetic \u003cstrong data-start=\"147\" data-end=\"185\"\u003emitochondria-targeted tetrapeptide\u003c\/strong\u003e composed of the amino acid sequence \u003cstrong data-start=\"222\" data-end=\"255\"\u003eD-Arg-dimethylTyr-Lys-Phe-NH₂\u003c\/strong\u003e. It belongs to the class of \u003cstrong data-start=\"284\" data-end=\"316\"\u003eSzeto–Schiller (SS) peptides\u003c\/strong\u003e, a group of small aromatic-cationic peptides designed to selectively localize within the \u003cstrong data-start=\"406\" data-end=\"438\"\u003einner mitochondrial membrane\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp data-start=\"441\" data-end=\"948\"\u003eUnlike many mitochondria-targeting compounds that rely on membrane potential, SS-31 interacts directly with \u003cstrong data-start=\"549\" data-end=\"564\"\u003ecardiolipin\u003c\/strong\u003e, a phospholipid unique to the inner mitochondrial membrane that plays a critical role in maintaining the structure and function of the \u003cstrong data-start=\"700\" data-end=\"734\"\u003eelectron transport chain (ETC)\u003c\/strong\u003e. Through this interaction, SS-31 has been studied for its ability to \u003cstrong data-start=\"804\" data-end=\"947\"\u003estabilize mitochondrial membranes, improve electron transport efficiency, and reduce mitochondrial reactive oxygen species (ROS) production\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp data-start=\"950\" data-end=\"1310\"\u003ePreclinical and clinical research has investigated SS-31 for its potential role in conditions associated with \u003cstrong data-start=\"1060\" data-end=\"1089\"\u003emitochondrial dysfunction\u003c\/strong\u003e, including metabolic disorders, cardiac ischemia-reperfusion injury, skeletal muscle fatigue, and age-related mitochondrial decline. In pharmaceutical development, the peptide is commonly referred to as \u003cstrong data-start=\"1293\" data-end=\"1309\"\u003eElamipretide\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp data-start=\"1312\" data-end=\"1539\"\u003eDue to its small size and cationic-aromatic structure, SS-31 is capable of \u003cstrong data-start=\"1387\" data-end=\"1442\"\u003erapid cellular uptake and mitochondrial penetration\u003c\/strong\u003e, allowing it to localize within mitochondria without requiring specialized transport mechanisms.\u003c\/p\u003e\n\u003cp data-start=\"1541\" data-end=\"1708\"\u003eSS-31 is typically manufactured using \u003cstrong data-start=\"1579\" data-end=\"1619\"\u003esolid-phase peptide synthesis (SPPS)\u003c\/strong\u003e and supplied in \u003cstrong data-start=\"1636\" data-end=\"1656\"\u003elyophilized form\u003c\/strong\u003e to preserve stability during storage and transport.\u003c\/p\u003e","brand":"EvoX Biotech Supplies LLC","offers":[{"title":"10 mg","offer_id":46592455803065,"sku":null,"price":78.0,"currency_code":"USD","in_stock":true},{"title":"10 vials with 10 mg","offer_id":46592455835833,"sku":null,"price":600.58,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0688\/1329\/1705\/files\/SS3110mg.jpg?v=1773014427","url":"https:\/\/evoxbiolabs.com\/products\/hgh-fragment-176-191-copy","provider":"EvoX Biotech Supplies LLC","version":"1.0","type":"link"}